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Latest research on AAT levels and Covid-19

The highest incidence of Covid per 100,000 population and highest death rate per million population is in the countries with the highest caucasian population and typically lowest AAT levels…

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Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys

Study objectives: Alpha1-antitrypsin (AAT) deficiency is a genetic disease that is widely known in Europe as a disease of white individuals, who, along with their descendants in other parts of the world, are at the highest risk for liver and/or lung disease…

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α1-Antitrypsin deficiency · 1: Epidemiology of α1-antitrypsin deficiency

In the last 40 years, following the publication of the seminal paper by Laurell and Eriksson,1 there have been significant advances in the understanding of genetic abnormalities related to α1-antitrypsin (AAT) deficiency and of the pathophysiology of the associated lung and liver diseases…

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Epidemiological correlation between COVID-19 epidemic and prevalence of α-1 antitrypsin deficiency in the world

Among 68 countries in the world, severity of the COVID-19 epidemic was correlated with the prevalence of α-1 antitrypsin (AAT) deficiency. For the severe variant, PI*Z, the correlation coefficient (CC) was 0.8584 for the number of patients and 0.8713 for the number of deaths. For the milder variant, PI*S, it was 0.5818 and 0.6326, respectively…

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α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action

The COVID-19 pandemic is a global emergency. Identifying populations who are at risk of severe complications is crucial in developing special measures to prevent or reduce severe illness and mortality in vulnerable patients…

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Indian scientists explain why Covid-19 spread is slower in Asia

According to the scientists, a deficiency of the protein Alpha-anti-trypsin (AAT) across the populations of Europe and North-America is one of the main factors that explain the rapid spread…

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A Mechanistic Link Between Selenium and Coronavirus Disease 2019 (COVID-19)

Coronavirus disease 2019 (COVID-19) is a rapidly emerging disease caused by a highly contagious virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and this disease has affected millions of people across the world and led to hundreds of thousands of deaths worldwide…

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Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

Higher rates of serious illness and death from coronavirus SARS-CoV-2 (COVID-19) infection among older people and those who have comorbidities suggest that age- and disease-related biological processes make such individuals more sensitive to environmental stress factors including infectious agents like coronavirus SARS-CoV-2. Specifically, impaired redox homeostasis and associated oxidative stress appear to be important biological processes that may account for increased individual susceptibility to diverse environmental insults…

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Supports Immune Health

Elderberry, vitamin C, zinc, echinacea, and L-glutathione were all studied to effectively boost the immune system.

Benefits of Elderberry. Elderberry immunity support study

  • Fights the Flu
  • May Reduces Cold Duration
  • Supports the immune system
  • Reduces Inflammation

Benefits of Vitamin C

  • Boosts the immune system
  • May help manage high blood pressure
  • Helps prevent iron deficiency

Benefits of Zinc

  • Immune function. The body needs zinc for the immune system to work properly
  • Can reduce the length and severity of common colds.

Benefits of Echinacea

  • Boosts the Immune System
  • Anti-Inflammatory Agent
  • Relieves Upper Respiratory Issues
  • Reduce cold symptoms and duration of cold
  • Help avoid the flu

Benefits of L-glutathione

  • supports a healthy immune system
  • May reduce respiratory disease symptoms.
  • Reduces oxidative stress
  • Improves insulin resistance
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Supports Lung Function

Selenized Yeast plays an important role in the health of your immune system.
Selenium Yeast helps with AAT deficiency and COPD. AAT is a protein that protects the lungs and liver from damage and supports Lung Function

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Supports Respiratory Health

Our blend of vitamin C, echinacea, L-glutathione, selenized yeast, and probiotics support your body’s regular respiratory system. By boosting your immune system it can give you a sense of wellbeing’while dealing with the stress in your daily life.

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Supports Cold & Flu

Zinc, echinacea, vitamin C, vitamin D, and elderberry. Studies have shown taking this combination of powerful supplements can reduce the duration of symptoms of infections like the common cold to keep you feeling healthy.

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Supports Good Gut Health

Our Blend of powerful probiotics can help to balance the friendly bacteria in your digestive system. Probiotics can help increase the beneficial bacteria population and maintain overall digestive health balance for well-being and gut health.

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Supports Weight Management

Studies have shown Lactobacillus Rhamnosus one of the strains in our probiotics blend may be the single best probiotic that may promote weight loss. We added vitamin D also to help support weight management and wellbeing.

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Delivers Important Nutrients

Essential nutrients are compounds that the body can’t make or can’t make in sufficient quantity. We use high potency ingredients such as Zinc, vitamin C, D, and L-glutathione. Each vitamin plays an important role in the body, and not getting enough of them can cause health problems and disease. our blend delivers Important Nutrients for overall health and wellbeing

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Healthy Skin Support

Our potent antioxidant blend of Zinc, elderberry, vitamin C, and vitamin D, helps to support healthy skin by lessening the formation of damaging free radicals and protects skin’s lipids (fats) and fibroblasts the cells that make collagen.

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SARS-CoV-2 mutation 614G creates an elastase cleavage site enhancing its spread in high AAT-deficient regions

SARS-CoV-2 was first reported from China. Within three months, it evolved to 10 additional subtypes. Two evolved subtypes (A2 and A2a) carry a non-synonymous Spike protein mutation (D614G). We conducted phylodynamic analysis of over 70,000 SARS-CoV-2 coronaviruses worldwide, sequenced until July2020, and found that the mutant subtype (614G) outcompeted the pre-existing type (614D), significantly faster in Europe and North-America than in East Asia…

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α1-Antitrypsin deficiency and the risk of COVID-19

The COVID-19 pandemic is a global emergency. Identifying populations who are at risk of severe complications is crucial in developing special measures to prevent or reduce severe illness and mortality in vulnerable patients.1 Emerging evidence indicates that alpha1-proteinase inhibitor might inhibit infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). α1-Antitrypsin also has anticoagulation effects…

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In plain sight: the role of alpha-1-antitrypsin in COVID-19 pathogenesis and therapeutics.

Entry of SARS-CoV-2 is facilitated by endogenous and exogenous proteases. These proteases proteolytically activate the SARS-CoV-2 spike glycoprotein and are key modulators of virus tropism. We show that SARS-CoV-2 naïve serum exhibits significant inhibition of SARS-CoV-2 entry. We identify alpha-1-antitrypsin (AAT) as the major serum protease inhibitor that potently restrict protease-mediated entry of SARS-CoV-2…

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Potential Use of Alpha-1 Anti-trypsin in the Covid-19 Treatment

The coronavirus disease-2019 (COVID-19), firstly originated in the city of Wuhan, Hubei Province, People’s Republic of China, is due to infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Guo et al., 2020). SARS-CoV-2 has shown high infectivity, and high mortality associated to respiratory failure from acute respiratory distress syndrome (ARDS), becoming rapidly a worldwide health emergency (Guo et al., 2020)…

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Among COVID-19 survivors, an increased risk of death, serious illness

As the COVID-19 pandemic has progressed, it has become clear that many survivors — even those who had mild cases — continue to manage a variety of health problems long after the initial infection should have resolved. In what is believed to be the largest comprehensive study of long COVID-19 to date, researchers at Washington University School of Medicine in St. Louis showed that COVID-19 survivors…

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Alpha-1 Antitrypsin Deficiency

What is alpha-1 antitrypsin deficiency? Alpha-1 antitrypsin deficiency (or AAT deficiency) is a genetic condition that can lead to lung and liver disease. People with AAT deficiency may develop emphysema (a serious lung disease) and liver cirrhosis (scarring of the liver). Symptoms of AAT deficiency can include shortness of breath and wheezing, chronic cough, recurrent lung infections, and jaundice (yellowing of the skin)…

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The lasting misery of coronavirus long-haulers

The lung scans were the first sign of trouble. In the early weeks of the coronavirus pandemic, clinical radiologist Ali Gholamrezanezhad began to notice that some people who had cleared their COVID-19 infection still had distinct signs of damage. “Unfortunately, sometimes the scar never goes away,” he says…

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Count the cost of disability caused by COVID-19

The COVID-19 pandemic is well into its second year, but countries are only beginning to grapple with the lasting health crisis. In March, a UK consortium reported that 1 in 5 people who were hospitalized with the disease had a new disability after discharge1. A large US study found similar effects for both hospitalized and non-hospitalized people2…

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